[Pharmwaste] Assessing cancer risks from chemicals

James Bukowski jbukowsk at jhmi.edu
Mon Jul 23 10:41:49 EDT 2007


Interesting resource.

The Carcinogenic Potency Database (CPDB) is a unique and widely used
international resource of results from 6153 chronic, long-term animal
cancer tests on 1485 chemicals. CPDB provides a standardized and easily
accessible database with qualitative and quantitative analyses of both
positive and negative experiments that have been published in the
general literature through 1997 and by the National Cancer
Institute/National Toxicology Program through 1998. 

*Overall, our HERP ranking shows that synthetic pesticide residues
rank low in possible carcinogenic hazard compared to many common
exposures. HERP values for some historically high exposures in the
workplace and some pharmaceuticals rank high, and there is an enormous
background of naturally-occurring rodent carcinogens in average
consumption of common foods. Results on this background of natural
chemicals cast doubt on the relative importance of low-dose exposures to
residues of synthetic chemicals such as pesticides.* 

http://potency.berkeley.edu/cpdb.html 

Rankings here.

http://potency.berkeley.edu/pdfs/herp.pdf 

Those in blue are naturally occurring.  Beer ranked much higher than
DDT (based on pre-1972 DDT exposures) for cancer risk.  Bummer.

Regards,



James Bukowski, CIH HEM
Environmental Health Officer
Virginia Tech (1980)
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