[Pharmwaste] RE: MARIJUANA INGREDIENTS

Andria Ventura aventura at cleanwater.org
Tue Sep 16 21:18:05 EDT 2008


This is intriguing for medical purposes, but regarding water, do we want
another antibacterial product in the water?  I wonder if these substances
could impact bacterial treatment for wastewater.  Isn't our message that
soap and water kills germs and we don't need to add antibacterial
substances?

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Subject: Pharmwaste Digest, Vol 35, Issue 3

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Today's Topics:

   1. Marijuana Ingredients Show Promise In Battling	Superbugs
      (DeBiasi,Deborah)
   2. Drugs in water affect 46 million in U.S.  (DeBiasi,Deborah)


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Message: 1
Date: Tue, 9 Sep 2008 11:14:48 -0400
From: "DeBiasi,Deborah" <dldebiasi at deq.virginia.gov>
Subject: [Pharmwaste] Marijuana Ingredients Show Promise In Battling
	Superbugs
To: <pharmwaste at lists.dep.state.fl.us>
Message-ID:
	<6C097DA58429B743A67070F98BE73A3702D7EFB2 at deqex01.deq.local>
Content-Type: text/plain;	charset="UTF-8"

Maybe a replacement for triclosan and triclocarbon?

****

http://www.sciencedaily.com/releases/2008/09/080908103045.htm

Marijuana Ingredients Show Promise In Battling Superbugs

ScienceDaily (Sep. 8, 2008) — Substances in marijuana show promise for
fighting deadly drug-resistant bacterial infections, including so-called
"superbugs," without causing the drug's mood-altering effects, scientists in
Italy and the United Kingdom are reporting.

Besides serving as infection-fighting drugs, the substances also could
provide a more environmentally-friendly alternative to synthetic
antibacterial substances now widely used in personal care items, including
soaps and cosmetics, they say. 

In the new study, Giovanni Appendino and colleagues point out that
scientists have known for years that marijuana contains antibacterial
substances. However, little research has been done on those ingredients,
including studies on their ability to fight antibiotic resistant infections,
the scientists say.

To close that gap, researchers tested five major marijuana ingredients
termed cannabinoids on different strains of methicillin-resistant
Staphylococcus aureus (MRSA), a "superbug" increasingly resistant to
antibiotics.

All five substances showed potent germ-killing activity against these
drug-resistant strains, as did some synthetic non-natural cannabinoids, they
say. The scientists also showed that these substances appear to kill
bacteria by different mechanisms than conventional antibiotics, making them
more likely to avoid bacterial resistance, the scientists note. At least two
of the substances have no known mood-altering effects, suggesting that they
could be developed into marijuana-based drugs without causing a "high."


----------------------------------------------------------------------------
----

Journal reference:

Appendino et al. Antibacterial Cannabinoids from Cannabis sativa: A
Structure−Activity Study. Journal of Natural Products, 2008; 71 (8): 1427
DOI: 10.1021/np8002673 
Adapted from materials provided by American Chemical Society.


Deborah L. DeBiasi
Email:   dldebiasi at deq.virginia.gov
WEB site address:  www.deq.virginia.gov
Virginia Department of Environmental Quality
Office of Water Permit Programs
Industrial Pretreatment/Toxics Management Program
PPCPs, EDCs, and Microconstituents
Mail:          P.O. Box 1105, Richmond, VA  23218 (NEW!)
Location:  629 E. Main Street, Richmond, VA  23219
PH:         804-698-4028
FAX:      804-698-4032


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Message: 2
Date: Fri, 12 Sep 2008 12:30:18 -0400
From: "DeBiasi,Deborah" <dldebiasi at deq.virginia.gov>
Subject: [Pharmwaste] Drugs in water affect 46 million in U.S. 
To: <pharmwaste at lists.dep.state.fl.us>
Message-ID:
	<6C097DA58429B743A67070F98BE73A37032E9D33 at deqex01.deq.local>
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