<html>
<head>
<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=us-ascii">
<meta name=Generator content="Microsoft Word 11 (filtered)">
<style>
<!--
/* Font Definitions */
@font-face
{font-family:"Comic Sans MS";
panose-1:3 15 7 2 3 3 2 2 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Times New Roman";}
h1
{margin-right:0in;
margin-left:0in;
font-size:24.0pt;
font-family:"Times New Roman";
font-weight:bold;}
a:link, span.MsoHyperlink
{color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{color:purple;
text-decoration:underline;}
p
{margin-right:0in;
margin-left:0in;
font-size:12.0pt;
font-family:"Times New Roman";}
p.Style2, li.Style2, div.Style2
{margin:0in;
margin-bottom:.0001pt;
text-align:center;
font-size:16.0pt;
font-family:Arial;
color:navy;
font-weight:bold;}
p.Style3, li.Style3, div.Style3
{margin:0in;
margin-bottom:.0001pt;
text-align:center;
font-size:16.0pt;
font-family:Arial;
color:navy;}
span.StyleArial11pt
{font-family:Arial;}
span.EmailStyle20
{font-family:"Comic Sans MS";
color:navy;
font-weight:normal;
font-style:normal;
text-decoration:none none;}
@page Section1
{size:8.5in 11.0in;
margin:1.0in 1.25in 1.0in 1.25in;}
div.Section1
{page:Section1;}
-->
</style>
</head>
<body lang=EN-US link=blue vlink=purple>
<div class=Section1>
<h1><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt'><a
href="http://cms.komen.org/komen/NewsEvents/KomenNews/070514_SilentSpring">http://cms.komen.org/komen/NewsEvents/KomenNews/070514_SilentSpring</a>
</span></font></b></h1>
<h1><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>Susan
G. Komen for the Cure Commissions Study on Environmental Factors Linked To
Breast Cancer<!--SS_END_SNIPPET(fragment8,2)--> </span></font></b></h1>
<!--START MAIN CONTENT HERE -->
<p><!--SS_BEGIN_OPENREGIONMARKER(region3)--><i><font size=3
face="Times New Roman"><span style='font-size:12.0pt;font-style:italic'>Study
Results Published in </span></font></i>Cancer<i><span style='font-style:italic'>;
Free Access Available to Mammary Carcinogens Database</span></i></p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>DALLAS - May 14, 2007<i><span style='font-style:italic'> - </span></i></span></font></b>Susan
G. Komen for the Cure and the Silent Spring Institute announce the publication
of Environmental Factors in Breast Cancer, the most comprehensive review to
date of scientific research on environmental factors that may increase breast
cancer risk. The study findings were released today in the online version of
the scientific journal <i><span style='font-style:italic'>Cancer</span></i>. A
hard copy version of the study will be published as a supplement to the June 15
edition of <i><span style='font-style:italic'>Cancer</span></i>.</p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>The
state-of-the-science review, commissioned by Komen for the Cure and conducted
by the Silent Spring Institute with additional researchers from Harvard
University, Roswell Park Cancer Institute and the University of Southern California, collected and assessed existing scientific reports on potential links
between specific environmental factors and breast cancer. </span></font></p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Researchers identify 216 chemicals that cause breast cancer
in animals</span></font></b><br>
The researchers synthesized national and international data sources and
identified 216 chemicals that cause breast tumors in animals. They used the
information to create a unique searchable online database featuring detailed
information on the carcinogens.</p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Free, searchable online database - carcinogens</span></font></b><br>
The database, accessible at <font color=blue><!-- TRANSIT - HYPERLINK --><!-- .http://www.komen.org/environment. --><span
style='color:blue'><a href="http://www.komen.org/environment" target="_top">www.komen.org/environment</a></span></font>,
is available free of charge and will be of particular interest to researchers,
healthcare workers, policymakers and some members of the public.</p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Komen's goal in funding the initiative</span></font></b><br>
Komen for the Cure's goal in funding the Silent Spring initiative was to
determine where there is consensus within the scientific community on the
relationship between environmental factors and breast cancer and where
additional research or improved research methods are needed. Such information
can help guide public policy and help funding organizations like Komen for the
Cure to determine where to most effectively target research grant monies.</p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Study details</span></font></b><br>
The database includes references to 900 studies, 460 of which are human breast
cancer studies that were critically evaluated by the research team. The studies
measure breast cancer risk related to body size, physical activity,
environmental pollutants, and prospective studies of diet.<font color=navy><span
style='color:navy'> </span></font>For each study, bibliographic information,
key methods and findings, and a critical assessment of the strength of the
evidence is included.</p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>The
database reveals that among the 216 compounds that cause breast tumors in
animals:</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-- 73
have been present in consumer products or as contaminants in food</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-- 35 are
air pollutants</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-- 25
have been associated with occupational exposures affecting more than 5,000
women a year</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-- 29 are
produced in the United States in large amounts, often exceeding 1 million
pounds per year.</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>"Komen
is eager to see quality science yield answers that will eventually lead us to
our ultimate goal of knowing how to prevent breast cancer. Commissioning this
study is a step toward that goal, because it helps to determine what is known
and what is not known about the possible link between certain environmental
factors and the incidence of breast cancer," said Hala Moddelmog,
president and CEO of Komen for the Cure. </span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>"While
it is disturbing to learn that there are so many chemicals that may be linked
to breast cancer, there is also a great opportunity to save thousands of lives
by identifying those links, limiting exposure and finding safer alternatives.
It is critical that we integrate this information into policies that govern
chemical exposures," said Julia G. Brody, PhD, executive director of the
Silent Spring Institute.</span></font></p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Silent Spring Institute examines lifestyle influences</span></font></b><br>
The Silent Spring Institute study also examined lifestyle influences on breast
cancer, such as physical activity and diet. The study results underscore the
importance of regular, life-long physical activity to lower a woman's risk of
developing breast cancer. The study concluded that further research is needed
to determine the relationship between dietary factors and breast cancer risk.</p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>Komen funds additional environmental projects</span></font></b><br>
In response to the study's findings, Komen is now funding the development of
new and innovative models for researching breast cancer and environmental risk
factors. Komen also continues to fund environmental projects as part of its
investigator-initiated grants program and is actively looking for ways to
partner with other research groups such as the U.S. Centers for Disease Control
and Prevention Environmental Health Labs.</p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>Susan G.
Komen for the Cure is committed to continuing its involvement in the
investigation of environmental factors related to breast cancer and is funding
a second phase of the Silent Spring Institute study. Phase two focuses on the
toxicology of endocrine disruptors, perinatal and early life exposures,
non-hormonal pharmaceuticals, tobacco smoke, occupational exposures, exposure
to light at night, and stress and social factors.</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>"As
an advocacy organization, Komen for the Cure is committed to educating people
about what we know about breast cancer today, while continuously searching for
evidence that will provide answers for tomorrow," said Moddelmog.</span></font></p>
<p><i><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-style:italic'>Cancer</span></font></i> is a journal of the American Cancer
Society.</p>
<p><b><font size=3 face="Times New Roman"><span style='font-size:12.0pt;
font-weight:bold'>About Silent Spring Institute</span></font></b><br>
Founded in 1994, Silent Spring Institute is a non-profit research organization
dedicated to studying the environment's effect on women's health, with an
emphasis on breast cancer. Silent Spring's groundbreaking research on endocrine
disrupting compounds and pollution in homes has been published in <i><span
style='font-style:italic'>Environmental Science & Technology, Environmental
Health Perspectives</span></i>, and other scientific journals. Silent Spring
Institute scientists work in partnership with physicians and public health
advocates, and researchers at Brown University, Harvard University, SUNY- Stony
Brook, and elsewhere. Funding for Silent Spring Institute's research is by
grants from the National Institutes of Health, National Science Foundation,
private foundations, and individual donors. For more information, please visit <u><!-- TRANSIT - HYPERLINK --><!-- .http://www.silentspring.org/. --><font
color=blue><span style='color:blue'><a href="http://www.silentspring.org/"
target="_top">www.silentspring.org</a>.</span></font></u></p>
<p class=MsoNormal><font size=3 color=navy face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:navy'> </span></font></p>
<p class=MsoNormal><strong><b><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'>Steven
Boggs; IDEM/OPPTA</span></font></b></strong></p>
<p class=MsoNormal><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'><a
href="http://www.in.gov/recycle/index.html">http://www.in.gov/recycle/index.html</a></span></font><font
color=navy face="Comic Sans MS"><span style='font-family:"Comic Sans MS";
color:navy'> </span></font></p>
<p class=MsoNormal><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'>800/988-7901
or 233-6660</span></font></p>
<p class=MsoNormal><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'>Fax:
317/233-5627</span></font></p>
<p class=MsoNormal><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'>100 N.
Senate Ave</span></font><font color="#004000" face="Comic Sans MS"><span
style='font-family:"Comic Sans MS";color:#004000'>, MC 64-01</span></font></p>
<p class=MsoNormal><font size=3 color="#004000" face="Comic Sans MS"><span
style='font-size:12.0pt;font-family:"Comic Sans MS";color:#004000'>Indianapolis</span></font><font
color="#004000" face="Comic Sans MS"><span style='font-family:"Comic Sans MS";
color:#004000'>, IN 46204-2251</span></font></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> </span></font></p>
</div>
</body>
</html>