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<P><B></B><A HREF="http://www.reutershealth.com/archive/2008/02/22/eline/links/20080222elin001.html"><B><U><FONT COLOR="#0000FF">http://www.reutershealth.com/archive/2008/02/22/eline/links/20080222elin001.html</FONT></U></B></A><B></B>
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<P><B><FONT FACE="Arial">Flour mill workers have fewer sons</FONT></B>
<BR><I><FONT FACE="Arial">Last Updated: 2008-02-22 10:24:37 -0400 (Reuters Health)</FONT></I>
<BR><FONT FACE="Arial">NEW YORK (Reuters Health) - A new study suggests that men who work in flour mills tend to father fewer sons than average -- adding to evidence that certain toxic exposures may affect men's reproductive function or the survival of male fetuses.</FONT></P>
<P><FONT FACE="Arial">Using data from the Washington State health department, researchers found that the children of men who worked in flour mills were disproportionately female. Of 59 children born to these workers between 1980 and 2002, 37 -- or roughly 63 percent -- were girls. </FONT></P>
<P><FONT FACE="Arial">In contrast, just over 51 percent of children born in Washington during that period were boys, according to the findings published in the American Journal of Industrial Medicine. </FONT></P>
<P><FONT FACE="Arial">While the reason for the discrepancy is not certain, on-the-job exposure to chemicals may be involved, according to Dr. Samuel Milham and Eric M. Ossiander, the health department researchers who conducted the study.</FONT></P>
<P><FONT FACE="Arial">Flour mill workers are exposed to a range of pesticides used to keep insects out of stored grains and flour. One pesticide, known as DBCP, has been banned because of its effects on men's fertility and on male births, Milham and Ossiander point out. </FONT></P>
<P><FONT FACE="Arial">The current findings suggest that some pesticides used in flour mills may have similar effects, the researchers speculate.</FONT></P>
<P><FONT FACE="Arial">Mother Nature has always given a slight advantage to males in the male-to-female birth ratio, as death rates among young males are higher. Traditionally, it's been expected that for every 100 girls born, there will be about 105 boys.</FONT></P>
<P><FONT FACE="Arial">However, recent research suggests that this gap is narrowing. One study found that, across the U.S. and Japan, male births have been declining since 1970. In the U.S., the proportion of males births dipped from 105.5 per 100 female births in 1970, to 104.6 in 2001. </FONT></P>
<P><FONT FACE="Arial">Those researchers speculated that environmental toxins -- whether pesticides, heavy metals, solvents or other pollutants -- may partially explain this trend. Men's exposure to these chemicals may, for example, specifically damage sperm carrying the Y chromosome, and this could lead to fewer male fetuses.</FONT></P>
<P><FONT FACE="Arial">Male fetuses themselves may also be more vulnerable to such toxins. </FONT>
<BR><FONT FACE="Arial">The current study found that, besides the low prevalence of male births, boys born to flour mill workers also weighed significantly less than average. Their average birthweight was 7 pounds, compared with nearly 8 pounds among girls born to flour mill workers, and about 7 pounds, 12 ounces among boys born statewide.</FONT></P>
<P><FONT FACE="Arial">According to Milham and Ossiander, this finding is "unprecedented," and could reflect another toxic effect of the fathers' chemical exposures. </FONT></P>
<P><FONT FACE="Arial">SOURCE: American Journal of Industrial Medicine, February 2008.</FONT>
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<P><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Deborah L. DeBiasi</FONT>
<BR><B><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Email: dldebiasi@deq.virginia.gov</FONT></B>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">WEB site address: </FONT><A HREF="file://www.deq.virginia.gov"><U></U><U><FONT COLOR="#0000FF" SIZE=2 FACE="Times New Roman">www.deq.virginia.gov</FONT></U></A>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Virginia Department of Environmental Quality</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Office of Water Permit Programs</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Industrial Pretreatment/Toxics Management Program</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">PPCPs, EDCs, and Microconstituents</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Mail: P.O. Box 1105, Richmond, VA 23218</FONT><B></B><B><I> <FONT COLOR="#FF0000" SIZE=2 FACE="Times New Roman">(NEW!)</FONT></I></B>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">Location: 629 E. Main Street, Richmond, VA 23219</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">PH: 804-698-4028</FONT>
<BR><FONT COLOR="#000080" SIZE=2 FACE="Times New Roman">FAX: 804-698-4032</FONT>
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