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<p class=MsoNormal><span style='font-size:11.0pt;color:#1F497D'>Comments from a
non-member:<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;color:#1F497D'><o:p> </o:p></span></p>
<div>
</div></div></DIV>
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<DIV STYLE="FONT-SIZE: 9pt; FONT-FAMILY: Courier New"><EM><FONT FACE="Arial" SIZE="2">The Department of Environmental
Protection values your feedback as a customer. DEP Secretary Michael W. Sole is committed to continuously assessing and
improving the level and quality of services provided to you. Please take a few minutes to comment on the quality of
service you received. <eXclaimer:HTML_ONLY>Simply click on <A TARGET="_blank" HREF="http://survey.dep.state.fl.us/?refemail=Laurie.Tenace@dep.state.fl.us">this link to the DEP Customer
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<DIV STYLE="FONT-SIZE: 9pt; FONT-FAMILY: Courier New"><div class=Section1><div><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in'>
<p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span
style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Edo McGowan
[mailto:</span> <span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>edo_mcgowan@hotmail.com]
<br>
<b>Sent:</b> Sunday, March 15, 2009 1:27 AM<br>
<b>To:</b> pharmwaste@lists.dep.state.fl.us<br>
<b>Subject:</b> RE: [Pharmwaste] WRF Study: Trace Pharms in Drinking Water Too
Lowto Impact Human Health<o:p></o:p></span></p>
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<p class=MsoNormal><o:p> </o:p></p>
<p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:10.0pt;
font-family:"Verdana","sans-serif"'>I would raise the same question I did at
the Research Triangle Environmental Health Collaborative (RTEHC) of November
10-11, 2008 on pharmaceuticals in water. That question was never answered---it
was----what impacts accrue to interactions with biofilms and pharmaceuticals in
water? How does that impact the levels of multi-drug resistance within sgedding
biofilms? When we also throw in antibiotic resistant genes which are not
affected by current levels of chlorine found in potable water supplies as well
as the fact that these genes are not stopped by typical filtering systems used
by potable water treatment, we have several unanswered questions. These are the
questions that needs to be addressed. One of the other scientists at the RTECH
also kept raising the question on fetal impacts and that question also was
consistently ignored. Thus, I think that there are a lot of serious unanswered
questions that are inconvenient for the industry to address.<br>
<br>
Dr Edo McGowan<br>
<br>
<br>
-----Original Message-----<br>
From: Pete Pasterz <PAPasterz@cabarruscounty.us><br>
To: pharmwaste@lists.dep.state.fl.us <pharmwaste@lists.dep.state.fl.us><br>
Sent: Fri, 13 Mar 2009 4:52 pm<br>
Subject: RE: [Pharmwaste] WRF Study: Trace Pharms in Drinking Water Too Low to
Impact Human Health<o:p></o:p></span></p>
<div id="EC_AOLMsgPart_0_58d0d85e-73f3-44e6-9af5-e9911c5d3a9c"><pre
style='background:white'><tt><span style='color:black'>Boy, what a relief!  I'm glad that they used the EPA's methods for determining </span></tt><span
style='color:black'><br>
<tt>Acceptable Daily Intake, because history has shown that this provides the </tt><br>
<tt>foolproof certainty needed to assure us that everything is OK with exposures of </tt><br>
<tt>every individual compound to adult male humans --even if the chemicals aren't </tt><br>
<tt>actually tested in and of themselves and in combination with one another.</tt><br>
<br>
<tt> Pete Pasterz, NCQRP</tt></span><tt><span style='font-family:Symbol;
color:black'>þ</span></tt><span style='color:black'><br>
<tt>Cabarrus County Recycling and HHW</tt><br>
<tt>PO BOX 707 </tt><br>
<tt>Concord, NC  28026</tt><br>
<tt>704-920-3280</tt><br>
<tt><a href="http://www.cabarruscounty.us/waste">www.cabarruscounty.us/waste</a></tt><br>
<tt>If you're not for ZERO Waste, how much Waste ARE you for?</tt><br>
<br>
<br>
<tt>-----Original Message-----</tt><br>
<tt>From: <a href="mailto:pharmwaste-bounces@lists.dep.state.fl.us">pharmwaste-bounces@lists.dep.state.fl.us</a> [<a
href="mailto:pharmwaste-bounces@lists%20%20..dep.state.fl.us?">mailto:pharmwaste-bounces@lists.dep.state.fl.us</a>] </tt><br>
<tt>On Behalf Of Bowling, Patrick</tt><br>
<tt>Sent: Thursday, March 12, 2009 4:40 PM</tt><br>
<tt>To: <a href="mailto:pharmwaste@lists.dep.state.fl.us">pharmwaste@lists.dep.state.fl.us</a></tt><br>
<tt>Subject: [Pharmwaste] WRF Study: Trace Pharms in Drinking Water Too Low to </tt><br>
<tt>Impact Human Health</tt><br>
<br>
<tt>(from: <a href="http://www.prweb.com/releases/2009/03/prweb2199124.htm">http://www.prweb.com/releases/2009/03/prweb2199124.htm</a>)</tt><br>
<br>
<tt>Levels of Trace Pharmaceuticals in Drinking Water Too Low to Impact Human Health </tt><br>
<tt>According to Water Research Foundation Study</tt><br>
<br>
<tt>The concentrations of pharmaceutical drugs and endocrine-disrupting compounds </tt><br>
<tt>found in our public drinking water are likely too low to impact human health, </tt><br>
<tt>according to a new report by the Water Research Foundation, the nation's leading </tt><br>
<tt>drinking water research organization.</tt><br>
<br>
<tt>Denver, CO (PRWEB) March 4, 2009 -- The concentrations of pharmaceutical drugs </tt><br>
<tt>and endocrine-disrupting compounds found in our public drinking water are likely </tt><br>
<tt>too low to impact human health, according to a new report by the Water Research </tt><br>
<tt>Foundation, the nation's leading drinking water research organization.</tt><br>
<br>
<tt>The Water Research Foundation presented its findings at a February 27 </tt><br>
<tt>congressional briefing.</tt><br>
<br>
<tt>Endocrine-disrupting compounds (EDCs) encompass a variety of chemical classes, </tt><br>
<tt>including hormones, plant constituents (phytoestrogens), pesticides, compounds </tt><br>
<tt>used in the plastics industry and in consumer products, and other industrial </tt><br>
<tt>by-products. There is20growing public attention and concern about the possibility </tt><br>
<tt>of health effects from trace amounts of EDCs and drugs that are flushed down the </tt><br>
<tt>toilet or enter the water supply through human and livestock waste. The Water </tt><br>
<tt>Research Foundation report examined not only the presence of trace levels of </tt><br>
<tt>EDCs and drugs in water, but explored if there is a potential link between the </tt><br>
<tt>levels of these compounds found in water and effects on human health.</tt><br>
<br>
<tt>Water Research Foundation has committed up to $1 million per year to an </tt><br>
<tt>integrated, multi-year research program to address specific issues associated </tt><br>
<tt>with ultra-low levels of drugs and chemicals in the water supply.</tt><br>
<br>
<tt>The report, titled Toxicological Relevance of Endocrine Disruptors and </tt><br>
<tt>Pharmaceuticals in Drinking Water, concludes three years of research in </tt><br>
<tt>collaboration with 17 water utilities.</tt><br>
<br>
<tt>"Even the most advanced treatment processes that we've studied won't achieve an </tt><br>
<tt>absolute zero level of contaminants," said study researcher Shane Snyder, Ph.D., </tt><br>
<tt>research and development project manager for Southern Nevada Water Authority. </tt><br>
<tt>"Therefore, it's vital that we look at the real risks before we spend a </tt><br>
<tt>tremendous amount of resources on the issue."</tt><br>
<br>
<tt>The study's objective was to inform water utilities, regulators, scientists, and </tt><br>
<tt>the public about the occurrence and potential human health relevance of </tt><br>
<tt>pharmaceuticals and EDCs in drinking water.</tt><br>
<br>
<tt>Research Methods and Selected Findings:</tt><br>
<br>
<tt>The Water Research Fo</tt><br>
<tt>undation research team first selected 62 representative </tt><br>
<tt>chemicals for further evaluation. The selection criteria included likelihood of </tt><br>
<tt>occurrence, production volume, toxicity, and analytical capability. The </tt><br>
<tt>scientists drew 300 water samples from 19 sites nationwide and analyzed them for </tt><br>
<tt>the selected suite of compounds using extremely sensitive analytical methods </tt><br>
<tt>with low part-per-trillion detection limits. The team conducted risk evaluations </tt><br>
<tt>assuming exposure through drinking water for all target pharmaceuticals, 10 of </tt><br>
<tt>the suspected EDCs, and three of the hormones. Acceptable daily intakes (ADIs) </tt><br>
<tt>were calculated using methods consistent with Environmental Protection Agency </tt><br>
<tt>approaches for determining levels of exposure to environmental contaminants that </tt><br>
<tt>are not likely to be associated with adverse health effects. To estimate the </tt><br>
<tt>exposure of these compounds via drinking water, the ADIs were then converted to </tt><br>
<tt>drinking water equivalent levels.</tt><br>
<br>
<tt>Key conclusions reported include the following:</tt><br>
<br>
<tt>* Of the 62 compounds analyzed, only three were consistently (>50 percent </tt><br>
<tt>frequency) found in the water samples</tt><br>
<br>
<tt>* Trace concentrations of 24 compounds were detectable in at least 20 percent of </tt><br>
<tt>raw (untreated) water samples</tt><br>
<br>
<tt>* Trace concentrations of 11 compounds were found in at least 20 percent of </tt><br>
<tt>finished (treated) drinking water samples. Five prescription drug-related </tt><br>
<tt>compounds were detected: atenolol, Dilantin, carbamazepine, gemfibrozil, and </tt><br>
<tt>sulfamethoxazole. The scientists also fou</tt><br>
<tt>nd trace amounts of atrazine (a widely </tt><br>
<tt>used herbicide), DEET (an active ingredient of insect repellants), metolachlor </tt><br>
<tt>(a pesticide), and two flame retardants used in consumer products, Tris </tt><br>
<tt>(2-chloroethyl) phosphate (TECP) and Tris (chloroisopropyl) phosphate (TCPP).</tt><br>
<br>
<tt>* The target compound detected at the highest concentration was atrazine. </tt><br>
<tt>Atrazine was detected at levels as high as 870 parts per trillion or nanograms </tt><br>
<tt>per liter (ng/l), less than a third of the federal regulatory limit of 3,000 </tt><br>
<tt>parts per trillion or ng/l. The median level of atrazine detected in the study </tt><br>
<tt>was 49 ng/l.</tt><br>
<br>
<tt>"Pharmaceuticals and EDCs can certainly be detected in water, and science will </tt><br>
<tt>continue to establish lower and lower detection limits," said Snyder. "Based on </tt><br>
<tt>the research done so far, they appear to occur at levels far below acceptable </tt><br>
<tt>daily intake levels."</tt><br>
<br>
<tt>"Concerns may be raised because detection of chemicals seems to be evidence </tt><br>
<tt>enough of risk," Snyder added. "But in the world of toxicology, it's the dose, </tt><br>
<tt>or amount of a substance, that can create a health risk. It's the concentration </tt><br>
<tt>that matters."</tt><br>
<br>
<br>
<tt>About the Water Research Foundation:</tt><br>
<tt>Founded in 1966, the Water Research Foundation is an international, 501c(3) </tt><br>
<tt>nonprofit organization that sponsors research to enable water utilities, public </tt><br>
<tt>health agencies and other professionals to provide safe and affordable drinking </tt><br>
<tt>water to the public. With more than 950 subscriber members who provide water for 0D</tt><br>
<tt>80 percent of the U.S. population, the Water Research Foundation has funded and </tt><br>
<tt>managed more than 1,000 projects. For more information, go to </tt><br>
<tt><a href="http://www.waterresearchfoundation.org/">www.WaterResearchFoundation.org</a>.</tt><br>
<br>
<tt>Contact:</tt><br>
<tt>Jill Estabrook Wisehart</tt><br>
<tt>Communications Director</tt><br>
<tt>303.347.6111</tt><br>
<br>
<tt># # #</tt><br>
<br>
<tt>=========================</tt><br>
<br>
<tt>G. Patrick Bowling, P.G. | Senior Geologist</tt><br>
<tt>PA Department of Environmental Protection</tt><br>
<tt>Rachel Carson State Office Building</tt><br>
<tt>400 Market Street | P.O. Box 8555</tt><br>
<tt>Harrisburg, PA 17105-8555</tt><br>
<tt>Phone: 717-772-4048 | Fax: 717-787-9549</tt><br>
<tt>Email: <a href="mailto:gbowling@state.pa.us">gbowling@state.pa.us</a>  <a
href="http://www.depweb.state.pa.us/">www.depweb.state.pa.us</a></tt><br>
<tt>---</tt><br>
<tt>Note: As a courtesy to other listserv subscribers, please post messages to the </tt><br>
<tt>listserv in plain text format to avoid the garbling of messages received by </tt><br>
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href="http://lists.dep.state.fl.us/cgi-bin/mailman/listinfo/pharmwaste">http://lists.dep.state.fl.us/cgi-bin/mailman/listinfo/pharmwaste</a> </tt><br>
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<tt>FOR PROBLEMS:  Contact List Administrator <a
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<tt>E-mail correspondence to and from this address may be subject to the North </tt><br>
<tt>Carolina Public Records Law and may be disclosed to third parties.</tt><br>
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href="http://lists.dep.state.fl.us/cgi-bin/mailman/roster/pharmwaste">http://lists.dep.state.fl.us/cgi-bin/mailman/roster/pharmwaste</a> </tt><br>
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<tt>FOR PROBLEMS:  Contact List Administrator <a
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<tt>SEND MAIL to the list server at:  <a
href="mailto:pharmwaste@lists.dep.state.fl.us">pharmwaste@lists.dep.state.fl.us</a></tt></span><span
style='font-size:9.0pt;color:black'><o:p></o:p></span></pre></div>
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