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<p class=MsoNormal><span style='font-size:11.0pt;color:#1F497D'><o:p>&nbsp;</o:p></span></p>

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<DIV STYLE="FONT-SIZE: 9pt; FONT-FAMILY: Courier New"><EM><FONT FACE="Arial" SIZE="2">The Department of Environmental Protection values your feedback as a customer. DEP Secretary Michael W. Sole is committed to continuously assessing and improving the level and quality of services provided to you. Please take a few minutes to comment on the quality of service you received. Simply click on <A HREF="http://survey.dep.state.fl.us/?refemail=Laurie.Tenace@dep.state.fl.us" TARGET="_blank">this link to the DEP Customer Survey</A>. Thank you in advance for completing the survey.</FONT></EM></DIV>
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<p class=MsoNormal style='margin-left:.5in'><b><span style='font-size:10.0pt;
font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;
font-family:"Tahoma","sans-serif"'> Cecilia Height [mailto:cheight@cfl.rr.com] <br>
<b>Sent:</b> Friday, May 14, 2010 2:25 AM<br>
<b>To:</b> pharmwaste-bounces@lists.dep.state.fl.us<br>
<b>Subject:</b> Bisphenol A's 'twin' may have more potent hormone effects<o:p></o:p></span></p>

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<p class=MsoNormal style='margin-left:.5in'><o:p>&nbsp;</o:p></p>

<p class=MsoNormal style='margin-left:.5in'><span style='font-size:14.0pt;
color:purple'><o:p>&nbsp;</o:p></span></p>

<p class=MsoNormal style='margin-left:.5in'><span style='font-size:14.0pt;
color:purple'><a href="http://www.sciencenews.org/view/generic/id/59113/title/Another_plastics_ingredient_raises_safety_concerns_">http://www.sciencenews.org/view/generic/id/59113/title/Another_plastics_ingredient_raises_safety_concerns_</a><o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";color:#14487E'>Another plastics
ingredient raises safety concerns <o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";color:#14487E'>Bisphenol A's 'twin'
may have more potent hormone effects<o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";color:#14487E'>By <a href="http://www.sciencenews.org/view/authored/id/18/name/Janet_Raloff">Janet
Raloff</a> <o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in;background:white'><span class=exclusiveprint><span style='font-family:"Verdana","sans-serif";
color:#14487E'>Web edition</span></span><span style='font-family:"Verdana","sans-serif";
color:#14487E'> : <acronym>Wednesday, May 12th, 2010</acronym> <o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in;background:white'><span class=print><span style='font-family:"Verdana","sans-serif";color:black'>Nonidentical twins</span></span><span class=descriptionprint><span style='font-family:"Verdana","sans-serif";
color:black'>BPA's structure resembles a pair of spectacles with two methyl, or
CH3, groups dangling from its bridge. In BPAF, the methyl groups' hydrogen
atoms are substituted with fluorines.</span></span><span class=creditprint><span style='font-family:"Verdana","sans-serif";color:black'>NIEHS</span></span><span style='font-family:"Verdana","sans-serif";color:black'><o:p></o:p></span></p>

<p style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";
color:black'>A largely ignored contaminant doesn&#8217;t just resemble bisphenol A,
the chemical found to leach out of hard plastic water bottles. It&#8217;s BPA&#8217;s
fluorinated twin &#8212; on steroids.<o:p></o:p></span></p>

<p style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";
color:black'>New laboratory studies in Japan indicate that the twin, called
bisphenol AF, or BPAF, may be even more potent than BPA in altering the effects
of steroid hormones such as estrogens in the body.<o:p></o:p></span></p>

<p style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";
color:black'>The unusual way that BPAF blocks some estrogen actions and fosters
others &#8220;could make this a vicious compound, a very toxic compound,&#8221; says
Jan-Åke Gustafsson, a molecular endocrinologist at the University of Houston.
The chemical is an ingredient of many plastics, electronic devices, optical fibers
and more.<o:p></o:p></span></p>

<p style='margin-left:.5in;background:white'><span style='font-family:"Verdana","sans-serif";
color:black'>&lt;snipped&gt;<o:p></o:p></span></p>

<p class=MsoNormal style='margin-left:.5in'><span style='font-size:14.0pt;
color:purple'><o:p>&nbsp;</o:p></span></p>

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