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<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/national/health-science/antibiotic-resistant-genes-are-widespread-in-nature-study-finds/2014/05/08/ec608662-d53c-11e3-aae8-c2d44bd79778_story.html?wpisrc=nl%5Fhdln">http://www.washingtonpost.com/national/health-science/antibiotic-resistant-genes-are-widespread-in-nature-study-finds/2014/05/08/ec608662-d53c-11e3-aae8-c2d44bd79778_story.html?wpisrc=nl%5Fhdln</a></span><o:p></o:p></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="6" color="black" face="Times New Roman"><span lang="EN" style="font-size:24.0pt;color:windowtext;font-weight:bold">Antibiotic-resistant genes are widespread in nature,
study finds<o:p></o:p></span></font></b></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">(Rocky Mountain Laboratories/ NIAID/NIH ) - Interaction of methicillin-resistant
staphylococcus aureus, MRSA, with a human white cell: Scientists discovered antibiotic-resistant genes like MRSA in 71 environments including oceans and human feces.<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:windowtext"><img border="0" width="549" height="404" id="Picture_x0020_1" src="cid:image001.jpg@01CF6B6D.DAAC0E70" alt="http://www.washingtonpost.com/rf/image_404h/2010-2019/WashingtonPost/2014/05/08/Health-Environment-Science/Images/Merlin_10173278.jpg"></span></font><font color="black"><span lang="EN" style="color:windowtext"><img border="0" width="32" height="32" id="_x0000_i1025" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1026" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1027" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1028" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1029" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1030" src="cid:image002.png@01CF6B6D.DAAC0E70"><img border="0" width="32" height="32" id="_x0000_i1031" src="cid:image002.png@01CF6B6D.DAAC0E70"><o:p></o:p></span></font></p>
<ul type="disc">
<li class="MsoNormal" style="color:windowtext;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l2 level1 lfo2">
<font size="3" face="Times New Roman"><span lang="EN" style="font-size:12.0pt"><o:p> </o:p></span></font></li></ul>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="4" color="black" face="Times New Roman"><span lang="EN" style="font-size:13.5pt;color:windowtext;font-weight:bold">By
<a href="http://www.washingtonpost.com/brady-dennis/2011/02/25/ABMgsCJ_page.html">
<font color="blue"><span style="color:blue">Brady Dennis</span></font></a>, Published: May 8<a href="mailto:brady.dennis@washpost.com?subject=Reader%20feedback%20for%20'Antibiotic-resistant%20genes%20are%20widespread%20in%20nature,%20study%20finds'"><font color="blue"><span style="color:blue">E-mail
the writer</span></font></a> <o:p></o:p></span></font></b></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">From Antarctic lakes to forest soil in Puerto Rico to the guts of mice,
scientists are finding antibiotic-resistant genes almost everywhere they look, according to a new study that examined environmental samples from around the globe.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">The findings, published Thursday in the journal
<a href="http://www.cell.com/current-biology/home"><font color="blue"><span style="color:blue">Current Biology</span></font></a>, revealed how widespread antibiotic-resistant genes are in nature. They also raised questions about how the prevalence of resistant
genes might relate to a major health problem: bacterial infections in humans that increasingly don’t respond to antibiotics.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Graphic<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/national/health-science/antibiotic-resistance-found-everywhere/2014/05/08/f6c5dcda-d6c5-11e3-8a78-8fe50322a72c_graphic.html"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="296" height="195" id="Picture_x0020_13" src="cid:image003.jpg@01CF6B6D.DAAC0E70" alt="Antibiotic resistance isn’t just a hospital phenomenon."></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/national/health-science/antibiotic-resistance-found-everywhere/2014/05/08/f6c5dcda-d6c5-11e3-8a78-8fe50322a72c_graphic.html"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="296" height="33" id="Picture_x0020_14" src="cid:image004.png@01CF6B6D.DAAC0E70" alt="Click Here to View Full Graphic Story"></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Antibiotic resistance isn’t just a hospital phenomenon.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">More on antibiotics<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="5" color="black" face="Times New Roman"><span lang="EN" style="font-size:18.0pt;color:windowtext;font-weight:bold"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/05/07/eight-things-you-can-do-today-to-help-stop-the-spread-of-killer-superbugs/"><font color="blue"><span style="color:blue">Eight
things you can do right now to help stop the spread of ‘superbugs’</span></font></a><o:p></o:p></span></font></b></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/05/07/eight-things-you-can-do-today-to-help-stop-the-spread-of-killer-superbugs/"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="90" height="60" id="Picture_x0020_15" src="cid:image005.jpg@01CF6B6D.DAAC0E70" alt="Eight things you can do right now to help stop the spread of ‘superbugs’"></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Lenny Bernstein MAY 7<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Bacteria resistant to medications are here now, and they are killing
people <o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="5" color="black" face="Times New Roman"><span lang="EN" style="font-size:18.0pt;color:windowtext;font-weight:bold"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/04/30/planet-headed-toward-post-antibiotic-era-when-treatments-dont-work-who/"><font color="blue"><span style="color:blue">Drug-resistant
bacteria around the globe threaten ‘achievements of modern medicine,’ WHO reports</span></font></a><o:p></o:p></span></font></b></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/04/30/planet-headed-toward-post-antibiotic-era-when-treatments-dont-work-who/"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="90" height="60" id="Picture_x0020_16" src="cid:image006.jpg@01CF6B6D.DAAC0E70" alt="Drug-resistant bacteria around the globe threaten ‘achievements of modern medicine,’ WHO reports"></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Lenny Bernstein APR 30<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">World is headed for a ‘post-antibiotic era’ when common infections
may be lethal<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="5" color="black" face="Times New Roman"><span lang="EN" style="font-size:18.0pt;color:windowtext;font-weight:bold"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/04/07/what-we-need-to-do-about-antibiotic-resistant-infections/"><font color="blue"><span style="color:blue">How
to fight back against drug-resistant infections</span></font></a><o:p></o:p></span></font></b></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/04/07/what-we-need-to-do-about-antibiotic-resistant-infections/"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="90" height="60" id="Picture_x0020_17" src="cid:image007.jpg@01CF6B6D.DAAC0E70" alt="How to fight back against drug-resistant infections"></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Steve Poretz APR 7<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Collaboration, funding are going to be critical to developing new antibiotics<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><b><font size="5" color="black" face="Times New Roman"><span lang="EN" style="font-size:18.0pt;color:windowtext;font-weight:bold"><a href="http://www.washingtonpost.com/opinions/antibiotic-resistance-is-a-huge-threat-to-human-health/2014/05/05/96b0279e-d23b-11e3-937f-d3026234b51c_story.html"><font color="blue"><span style="color:blue">The
bugs are coming</span></font></a><o:p></o:p></span></font></b></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><span style="font-size:12.0pt"><a href="http://www.washingtonpost.com/opinions/antibiotic-resistance-is-a-huge-threat-to-human-health/2014/05/05/96b0279e-d23b-11e3-937f-d3026234b51c_story.html"><font color="blue"><span style="color:blue;text-decoration:none"><img border="0" width="90" height="60" id="Picture_x0020_18" src="cid:image008.jpg@01CF6B6D.DAAC0E70" alt="The bugs are coming"></span></font></a></span></font><font color="black"><span lang="EN" style="color:windowtext"><o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Editorial Board MAY 5<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Antibiotic resistance extends around the world, demanding a global
response.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">“While the environment is known to harbor antibiotic-resistant strains
of bacteria, as proven by many preceding studies, we did not really know the extent of their abundance,”
<a href="http://www.genomenviron.org/People/Nesme.html"><font color="blue"><span style="color:blue">Joseph Nesme</span></font></a>, one of the study’s authors and a researcher at the University of Lyon in France, said in an announcement about the findings.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">To try to determine the prevalence of antibiotic-resistant genes, scientists
tapped into a growing reservoir of public data to compare DNA samples found in nature with those of “superbugs” that have infected patients in hospitals. Ultimately, researchers discovered antibiotic-resistant genes in 71 environments, from human feces to
English prairies.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Scientists have long known that antibiotic-resistant genes are present
in nature. Such organisms existed long before human beings began using bacteria in the environment to help produce the life-saving antibiotics now used throughout the world.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Most of the genes are benign, with little potential for making the
leap to animals and humans. But sometimes that transfer does happen.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">“What we’re seeing more and more of, that’s unquestionably true, is
that these resistant genes are becoming more and more abundant in pathogens” that can then carry antibiotic resistance to new organisms, said Lance Price, an epidemiologist and expert in antibiotic resistance at George Washington University. “They are getting
incorporated into organisms that they never were in before.”<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Once that happens, resistant genes tend to thrive and multiply, given
their ability to adapt and to stand up to certain antibiotics. Scientists are working to decipher precisely how — and how often — resistant genes in nature find their way into pathogens such as E. coli that can carry them on to humans and animals, with grave
health consequences.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">“It is only with more knowledge on antibiotic resistance dissemination”
— from the environment to the clinic — “that we will be able to produce more sustainable antibiotic drugs,” Nesme said.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">The publication of the study comes amid mounting concern that the planet
could be barreling toward a post-antibiotic era in which common infections might once again prove fatal as the antibiotics used to treat them become less and less effective.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">“The problem is so serious that it threatens the achievements of modern
medicine,” the World Health Organization <a href="http://www.washingtonpost.com/news/to-your-health/wp/2014/04/30/planet-headed-toward-post-antibiotic-era-when-treatments-dont-work-who/">
<font color="blue"><span style="color:blue">concluded in a report last week</span></font></a>.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">The WHO documented “very high rates of resistance” in different parts
of the globe: Some urinary tract infections and skin wounds, once easily treatable with common antibiotics, are proving more and more difficult to defeat. The bacteria that cause pneumonia are now less susceptible to penicillin. In dozens of countries, the
last-resort treatment for gonorrhea is losing its punch. Meanwhile, few new antibiotics are in the development pipeline.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">Despite the prevalence of antibiotic-resistant genes in nature, Price
said that the growing threats in human medicine are largely rooted in human misuse of antibiotics, and that the solutions lie in human hands.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">In September, the Centers for Disease Control and Prevention
<a href="http://www.cdc.gov/drugresistance/threat-report-2013/"><font color="blue"><span style="color:blue">warned</span></font></a> that the nation faces “potentially catastrophic consequences” if it does not move rapidly to counter the growing threat of antibiotic-resistant
infections, which sicken about 2 million Americans and kill an estimated 23,000 each year.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">The agency noted that the overuse of antibiotics is the strongest contributing
factor to the surge in resistance around the world — the more germs are exposed to an antibiotic, the more they are able to build resistance to it — and it has pushed for doctors and hospitals to be more judicious in their prescribing of the drugs.<o:p></o:p></span></font></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto"><font size="3" color="black" face="Times New Roman"><span lang="EN" style="font-size:12.0pt;color:windowtext">At the same time, the overwhelming majority of antibiotics in the United
States are used in animal agriculture, both to promote growth and to treat and prevent disease in livestock. In December, the Food and Drug Administration
<a href="http://www.washingtonpost.com/national/health-science/fda-finalizes-voluntary-rules-on-phasing-out-certain-antibiotics-in-livestock/2013/12/11/e64ca05c-61e8-11e3-8beb-3f9a9942850f_story.html">
<font color="blue"><span style="color:blue">asked the agricultural industry to voluntarily</span></font></a> phase out the use of certain antibiotics in livestock and prevent their use merely to boost animal growth. The move was intended to address long-standing
fears that the massive amounts of antibiotics being used on farms were making those medications less effective over time.<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
<p class="MsoNormal"><font size="2" color="navy" face="Times New Roman"><span style="font-size:10.0pt;color:navy">Deborah L. DeBiasi</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><b><font size="2" color="navy"><span style="font-size:10.0pt;color:navy;font-weight:bold">Email: Deborah.DeBiasi@deq.virginia.gov</span></font></b><b><i><font size="2" color="red"><span style="font-size:10.0pt;color:red;font-weight:bold;font-style:italic"><br>
</span></font></i></b><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">WEB site address:
<a href="http://www.deq.virginia.gov/">www.deq.virginia.gov</a></span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">Virginia Department of Environmental Quality</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">Office of Water Permits
</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">Industrial Pretreatment/Whole Effluent Toxicity (WET) Program</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">PPCPs, EDCs, and Microconstituents<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" color="navy" face="Times New Roman"><span style="font-size:11.0pt;color:navy"><a href="http://www.deq.virginia.gov/Programs/Water/PermittingCompliance/PollutionDischargeElimination/Microconstituents.aspx">http://www.deq.virginia.gov/Programs/Water/PermittingCompliance/PollutionDischargeElimination/Microconstituents.aspx</a></span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy"><o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="2" color="navy" face="Times New Roman"><span style="font-size:10.0pt;color:navy">Mail: P.O. Box 1105, Richmond, VA 23218</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">Location: 629 E. Main Street, Richmond, VA 23219</span></font><font size="2" color="navy"><span style="font-size:11.0pt;color:navy"><br>
</span></font><font size="2" color="navy"><span style="font-size:10.0pt;color:navy">PH: 804-698-4028 FAX: 804-698-4032<o:p></o:p></span></font></p>
<p class="MsoNormal"><font size="3" color="#000099" face="Times New Roman"><o:p> </o:p></font></p>
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