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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">It would also be interesting to see if they lived longer in a predator rich environment, which is more likely to occur in the wild. If they remain “care-free,”
they may succumb more readily to predation. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial","sans-serif";color:#1B1B1B">For example, the perch were believed to be less anxious and more comfortable in a predator-free environment, causing them to travel and search for food away from their pack.</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Best regards,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-autospace:none"><b><span style="font-size:11.0pt;font-family:"Trebuchet MS","sans-serif";color:#00693C">Charlotte A. Smith, R. Ph., M.S.</span></b><span style="font-size:11.0pt;font-family:"Trebuchet MS","sans-serif";color:#00693C"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Trebuchet MS","sans-serif";color:black">Senior Regulatory Advisor, PharmEcology Services<o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:windowtext">From:</span></b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:windowtext"> pharmwaste-bounces@lists.dep.state.fl.us [mailto:pharmwaste-bounces@lists.dep.state.fl.us]
<b>On Behalf Of </b>Catherine Zimmer<br>
<b>Sent:</b> Monday, August 11, 2014 11:09 AM<br>
<b>To:</b> 'DeBiasi, Deborah (DEQ)'; pharmwaste@lists.dep.state.fl.us<br>
<b>Subject:</b> RE: [Pharmwaste] Fish exposed to anti-anxiety meds live longer, better lives<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Hi all,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Now there is a anthropomorphized headline if I ever saw one. Good thing the authors came to their senses in the text of the article.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Very truly yours,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Catherine Zimmer, MS, BSMT<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Zimmer Environmental Improvement, LLC<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">St. Paul, MN
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Ph: 651.645.7509<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><a href="mailto:zenllc@usfamily.net">zenllc@usfamily.net</a><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:windowtext">From:</span></b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:windowtext">
<a href="mailto:pharmwaste-bounces@lists.dep.state.fl.us">pharmwaste-bounces@lists.dep.state.fl.us</a> [<a href="mailto:pharmwaste-bounces@lists.dep.state.fl.us">mailto:pharmwaste-bounces@lists.dep.state.fl.us</a>]
<b>On Behalf Of </b>DeBiasi, Deborah (DEQ)<br>
<b>Sent:</b> Monday, August 11, 2014 10:45 AM<br>
<b>To:</b> <a href="mailto:pharmwaste@lists.dep.state.fl.us">pharmwaste@lists.dep.state.fl.us</a><br>
<b>Subject:</b> [Pharmwaste] Fish exposed to anti-anxiety meds live longer, better lives<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><a href="http://www.pbs.org/newshour/rundown/fish-exposed-anti-anxiety-meds-live-longer-better-life/">http://www.pbs.org/newshour/rundown/fish-exposed-anti-anxiety-meds-live-longer-better-life/</a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="margin-right:.15pt;background:white"><b><span style="font-size:11.5pt;font-family:"Arial","sans-serif";color:#1B1B1B;text-transform:uppercase"><a href="http://www.pbs.org/newshour/topic/science/"><span style="color:#1B1B1B;text-decoration:none">Science</span></a>
<o:p></o:p></span></b></p>
<p class="MsoNormal" style="mso-margin-top-alt:8.05pt;margin-right:.15pt;margin-bottom:8.05pt;margin-left:0in;background:white">
<b><span style="font-size:24.0pt;font-family:"Arial","sans-serif";color:#1B1B1B">Fish exposed to anti-anxiety meds live longer, better lives<o:p></o:p></span></b></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-bottom:6.0pt;background:white">
<b><span style="font-family:"Arial","sans-serif";color:white"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-right:.15pt;background:white"><span style="font-family:"Arial","sans-serif";color:#1B1B1B">BY
<a href="http://www.pbs.org/newshour/author/dave-sloan/"><span style="color:#377BDA;text-decoration:none">Dave Sloan</span></a>
<i>August 8, 2014 at 4:32 PM EDT</i><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-right:.15pt;background:white"><span style="font-family:"Arial","sans-serif";color:#1B1B1B"><img border="0" width="689" height="458" id="Picture_x0020_1" src="cid:image001.jpg@01CFB559.FB6F0EB0" alt="European perch. Photo courtesy of Wikimedia Commons."><o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">European perch. Photo courtesy of Wikimedia Commons.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-right:.15pt;background:white"><span style="font-family:"Arial","sans-serif";color:#1B1B1B"><br>
A study<a href="http://iopscience.iop.org/1748-9326/9/8/084003/article?_ga=1.8786231.327671969.1407421678"><span style="color:#377BDA;text-decoration:none"> released on Friday</span></a> revealed that young fish live longer after being exposed to anti-anxiety
medicine concentrated in sewage runoffs.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">Past studies on the consequences of other compounds found in streams and waterways such as caffeine, estrogen, and diabetes medicine showed that they were potentially altering the reproductive systems
of fish living in the affected areas.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">Scientists tested to see if the exposure to
<a href="http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html"><span style="color:#377BDA;text-decoration:none">Oxazepam</span></a>, an anti-anxiety and insomnia medication, was impacting the survival rate among Eurasian perch. They tested adult and
embryos of the species by exposing them to several levels the sedative. The result concluded that both groups had a significantly higher survival rate than the studies non-exposed control group.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">The therapeutic effect of the drug also caused a noticeable change in the species’ behavior. For example, the perch were believed to be less anxious and more comfortable in a predator-free environment,
causing them to travel and search for food away from their pack. The change in their behavior led to a higher feeding rate than the unexposed fish.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">Researchers are concerned about the shift in behavior and increased longevity of the exposed fish. Baby Eurasian perch typically have a
<a href="http://iopscience.iop.org/1748-9326/9/8/084003/article?_ga=1.8362544.327671969.1407421678%20">
<span style="color:#377BDA;text-decoration:none">92 percent mortality rate </span>
</a>at hatching but the change in survival rate might potentially alter the the ecosystem.<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">Tomas Bodin, one of the co-authors of the study,
<a href="http://www.pbs.org/newshour/rundown/fish-exposed-anti-anxiety-meds-live-longer-better-life/%20http:/qz.com/246792/sewage-spiked-with-anti-anxiety-meds-helps-baby-fish-live-longer-mellower-lives/#/">
<span style="color:#377BDA;text-decoration:none">explained</span></a>, “A therapeutic effect leading to increased survival of one species may generate a proportional increase in mortality of that species’ prey, which may have cascading ecological consequences
that need consideration.”<o:p></o:p></span></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;margin-right:.15pt;mso-margin-bottom-alt:auto;background:white">
<span style="font-family:"Arial","sans-serif";color:#1B1B1B">The study has opened a conversation among the research community to take a further look into the long-term effects on fish and wildlife exposed to other human compounds.<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:navy">Deborah L. DeBiasi</span><span style="font-size:11.0pt;color:navy"><br>
</span><b><span style="font-size:10.0pt;color:navy">Email: <a href="mailto:Deborah.DeBiasi@deq.virginia.gov">Deborah.DeBiasi@deq.virginia.gov</a></span></b><b><i><span style="font-size:10.0pt;color:red"><br>
</span></i></b><span style="font-size:10.0pt;color:navy">WEB site address: <a href="http://www.deq.virginia.gov/">
www.deq.virginia.gov</a></span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">Virginia Department of Environmental Quality</span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">Office of Water Permits </span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">Industrial Pretreatment/Whole Effluent Toxicity (WET) Program</span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">PPCPs, EDCs, and Microconstituents<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;color:navy"><a href="http://www.deq.virginia.gov/Programs/Water/PermittingCompliance/PollutionDischargeElimination/Microconstituents.aspx">http://www.deq.virginia.gov/Programs/Water/PermittingCompliance/PollutionDischargeElimination/Microconstituents.aspx</a></span><span style="font-size:10.0pt;color:navy"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:navy">Mail: P.O. Box 1105, Richmond, VA 23218</span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">Location: 629 E. Main Street, Richmond, VA 23219</span><span style="font-size:11.0pt;color:navy"><br>
</span><span style="font-size:10.0pt;color:navy">PH: 804-698-4028 FAX: 804-698-4032<o:p></o:p></span></p>
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<HR><P><STRONG><SPAN style="FONT-SIZE: 12pt; COLOR: green; FONT-FAMILY: Arial">Recycling is a good thing. Please recycle any printed emails. <p></p></SPAN></STRONG></P></P>
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