[Pharmwaste] Excretion info: Aprepitant (Emend from Merck)

Terri Buckner tbuckner at ibiblio.org
Wed Feb 10 11:00:29 EST 2010

The patient info sheet, Metabolism section, from this drug says:

Following administration of a single IV 100-mg dose of [14C]-aprepitant
prodrug to healthy subjects, 57% of the radioactivity was recovered in urine
and 45% in feces. A study was not conducted with radiolabeled capsule

Does this mean that 43% is excreted in urine and 55% in feces?

This is a drug used by cancer patients for nausea control.
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