[Pharmwaste] Re: Pharmaceutical waste generation

[JuMullot at aol.com]

Dear colleagues, 
 
A partial answer to the question posed by Bill Brewer.
 
3 years ago I realized an evaluation (simple box model) of pharmaceutical  
waste generation through the unmetabolized fraction excreted by patients from a  
middle-size generalist hospital located in France. I found the following 
figures  :
 
- wastewater 750-1000 liters per day and per occupied bed,
 
- total pharmaceuticals ~ 2 to 2.5 kg per year and per occupied bed,  among 
them 85% from top 20 molecules. For example :
* 400 g per year and per occupied bed for total antibiotics (among  them ~ 
100 g of amoxicillin and ~ 5 g of ciprofloxacin)
* 600 g per year and per occupied bed for acetaminophen
* 600 g per year and per occupied bed for lactulose !
 
- 3.5 g per year and per occupied bed for total antineoplastic drugs  (higher 
loads for 5-fluorouracil, cyclophosphamid, ifosfamid, platinum salts and  
methotrexate)
 
I already remark that these raw evaluations were not so far (less than 1  
order of magnitude) from other modelisations or analytical determinations made  
in european hospital wastewater.
 
I remain at your disposal for any question about this subject (my current  
doctorat) and I hope you receive rainfalls at Durham (and elsewhere needed)  !
 
Best regards,
 
Jean Ulrich MULLOT
Laboratoire Santé Publique Environnement
Faculté de Pharmacie de Chatenay Malabry
Université Paris Sud 11





   
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