[Pharmwaste] Our Stolen Future - good book about endocrine disruptors

Fri Jul 27 09:30:46 EDT 2012

For many years the website http://ourstolenfuture.org/ has been a source for updated information relevant to this issue.

Rick Reibstein
Manager, Outreach and Policy
Office of Technical Assistance and Technology
Executive Office of Energy and Environmental Affairs
Commonwealth of Massachusetts
100 Cambridge St., 9th Floor
Boston, MA 02114
617 626 1062

From: pharmwaste-bounces at lists.dep.state.fl.us [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Tenace, Laurie
Sent: Thursday, July 26, 2012 4:00 PM
To: pharmwaste at lists.dep.state.fl.us
Subject: [Pharmwaste] Our Stolen Future - good book about endocrine disruptors

Please note that this email originated with Chen Wen at EPA.

I'll also vouch for this book. Thanks for reminding us.

Laurie

For folks who are interested in learning more about endocrine disruptors, an excellent book is "Our Stolen Future" by Theo Colborn. Ms. Colborn wrote the book many years ago, and was among the first to identify the potential dangers of endocrine disruptors, and the notion that sometimes it is not the dose, but the bio-availability of a partucilar substance - that makes the poison.

Chen H. Wen
Office of Prevention, Pesticides and Toxics
U.S. Environmental Protection Agency
202-564-8849 (ph)
202-564-8899 (fx)

----- Forwarded by Chen Wen/DC/USEPA/US on 07/26/2012 03:49 PM -----

From: pharmwaste-request at lists.dep.state.fl.us<mailto:pharmwaste-request at lists.dep.state.fl.us>
To: pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Date: 07/26/2012 03:27 PM
Subject: Pharmwaste Digest, Vol 81, Issue 10
Sent by: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us>

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Today's Topics:

1. RE: What's in the Water We Drink - long article about DC's
water (Miller, Christine M.)
2. RE: What's in the Water We Drink - long article about DC's
water (Volkman, Jennifer (MPCA))
3. FW: [Pharmwaste] What's in the Water We Drink - long article
about DC's water (Bunnell, Ross)
4. RE: What's in the Water We Drink - long article about DC's
water (Jim Mullowney)

----- Message from "Miller, Christine M." <Chris.Miller at outagamie.org<mailto:Chris.Miller at outagamie.org>> on Thu, 26 Jul 2012 18:28:59 +0000 -----
To:

"Fredrick L. Miller" <millerfl at tricity.wsu.edu<mailto:millerfl at tricity.wsu.edu>>, "pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>" <pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>>

Subject:

RE: [Pharmwaste] What's in the Water We Drink - long article about DC's water

Amen!

Christine Miller l Recycling Coordinator
1419 Holland Rd. l Appleton, WI 54911
Phone: 920-968-5721 l Fax: 920-788-4130
www.RecycleMoreOutagamie.org<http://www.RecycleMoreOutagamie.org>

-----Original Message-----
From: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us> [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Fredrick L. Miller
Sent: Thursday, July 26, 2012 1:26 PM
To: pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Subject: RE: [Pharmwaste] What's in the Water We Drink - long article about DC's water

"evidence suggests that the same contaminants that caused massive fish kills and deformities in recent years are linked to increases in obesity, diabetes, autism, cancer, and other disorders-and that medications and products we use every day might contribute to the problem"

I'm hoping someone way smarter than me in the field of toxicology can help me with a question.

We've heard since the time of Paracelsus "the dose makes the poison" yet we accept statements such as the one above at face value. How is it consuming such dilute levels of substances can cause all these ills while consuming much higher concentrations is considered therapeutic? Shouldn't we be much more concerned about consuming and applying the prescriptions, potions, lotions, and neat substances in full strength? After all, that "witch's brew" comes from our home to begin with. We dose ourselves there with little to no regard for interaction. There is no agency watching out for our safety when it comes to considering what happens when we mix our medications with our shampoos, perfumes, household cleaners, plasticizers, fuels, etc. in the home yet we're all wrapped around the axle about a few PPT of the stuff in our drinking water. Isn't that a bit like having our cart before our horse?

Fred

P.s. I get that the fish and frogs can't protect themselves but using the drinking water concentrations as the lead-off for the story just strikes me as sensationalism and fearmongering.

-----Original Message-----
From: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us> [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Tenace, Laurie
Sent: Wednesday, July 25, 2012 4:57 AM
To: pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Subject: [Pharmwaste] What's in the Water We Drink - long article about DC's water

Much more at the link.

http://www.washingtonian.com/articles/people/whats-in-the-water-we-drink-2/

Washington's tap water, most of which comes from the Potomac River, meets or exceeds federal water-quality standards. But new pollutants have emerged that are not removed by current water-purification technology. Evidence suggests that the same contaminants that caused massive fish kills and deformities in recent years are linked to increases in obesity, diabetes, autism, cancer, and other disorders-and that medications and products we use every day might contribute to the problem.

Of all the natural resources in the Washington area, none is more important than the potomac river. Besides the beauty and recreation it provides, the area pulls nearly 400 million gallons of water a day out of it-about 90 percent of our drinking water.

In some ways, the Potomac is cleaner today than it was 40 or 50 years ago. Back then, people were warned not to swim in the river or eat fish from it; a tetanus vaccination was recommended for anyone who did swim there. On many days, you could smell the Potomac before you saw it.

Improvements in wastewater treatment and conservation upgraded the water quality of the river, which wends its way nearly 500 miles from its origin in the Appalachian Plateau to Point Lookout, Maryland, where it empties into the Chesapeake Bay. These efforts helped reduce major pollutants-such as nitrogen and phosphorous from fertilizers, pesticides, and soaps-that fed algae, rootless plant-like organisms that grow in sunlit water. Algae blooms-rapid accumulations of microscopic algae in water that can stretch for miles-deplete the water of oxygen and release harmful toxins. They can virtually destroy a river if left to grow unchecked.

Despite this progress, the river is not "clean." In 2011, the Potomac Conservancy, an organization that monitors the river, gave the Potomac a grade of D, a drop from the D-plus the organization assigned it in 2007. The conservancy noted that more than a third of the estimated 10,000 stream miles in the Potomac watershed are threatened or impaired.

Even so, the drinking water in the Washington area is closely monitored and meets or exceeds every Environmental Protection Agency water-quality standard. But as some of the old pollutants have been removed from the river, new ones have emerged that are not removed by current technology and may be harmful to human health, especially for the very young.

This emerging class of contaminants, called endocrine-disrupting compounds (EDCs), a variety of natural and manmade chemicals from many sources, first came to light in a dramatic way in the summer and fall of 2002 with massive fish kills along the south branch of the Potomac River in West Virginia, about 200 miles upstream from DC. Some of the contaminants are new, and others have been discovered recently because new measuring techniques permit scientists to identify EDCs in minute quantities.

Says Luke Iwanowicz, a scientist with the US Geological Survey: "Many of these emerging contaminants have been off our radar until now, mostly because we did not have the ability to detect them."

Jeff Kelble ran a fishing-guide business on the Shenandoah River, long considered one of the nation's great fishing rivers, especially for smallmouth bass. The Shenandoah empties into the Potomac at Harpers Ferry, West Virginia. Kelble remembers when fish were so plentiful that they fought over his lures-it wasn't uncommon for the sport fishermen he guided to catch 50 to 60 fish in a day, all of which Kelble released back into the river.

That changed in the last week of March 2004, when Kelble learned that fish kills had struck the north fork of the Shenandoah. From his boat, when the murky spring water was clear enough, Kelble could see redbreast sunfish and smallmouth bass lying motionless on the riverbed.

Kelble didn't know what to make of the scene. Had a poison been dumped into the river? Was this fish kill related to the kills that had struck the south branch of the Potomac in 2002 and 2003? Had a large quantity of milk somehow found its way into the water from dairy farms along the riverbank? Milk has a voracious appetite for oxygen and might have robbed the river of enough to kill the fish, but when the river's oxygen levels were measured, they were normal.

Kelble tried catching fish but had little luck. Finally, he hooked a smallmouth bass.

"We were excited at first," Kelble says, "but when we lifted the fish out of the water, we saw it was covered with red sores that looked like cigar burns, and it had lost many of its scales. I'd never seen anything like it. I have an engineering degree-I'm not a biologist-and I had no idea what was wrong. We caught a few other fish, and almost all had similar sores on them." Kelble caught more fish. "Between 50 and 60 percent of the fish had lesions," he says.

Kelble, now a conservationist with Potomac Riverkeeper-a nonprofit that monitors river quality throughout the four-state Potomac watershed-estimates that in 2004 and 2005, 80 percent of the adult smallmouth-bass population was wiped out in the Shenandoah River. The bass are back, Kelble says, but he still sees sick fish.

Vicki Blazer, a fish pathologist with the US Geological Survey (USGS), had the job of finding the cause of the fish kills. Working out of Kearneysville, West Virginia, Blazer led a team onto the rivers to collect dead and dying fish. Electroshocks in the water stunned the fish and brought them to the surface, where Blazer's group netted them and put them into water buckets to which an anesthetic was added.

As Blazer dissected scores of smallmouth bass, she was surprised to find that many of the males had characteristics of both sexes. Some 80 percent of the male fish had oocytes-precursors of egg cells produced by females-in their testes, a condition known as intersex.

Intersex among some species of fish is not unheard of but, Blazer says, "you just don't see this intersex phenomenon with bass."

Ed Merrifield, president of Potomac Riverkeeper, calls the river fish kills "the canary in the coal mine."

Our region is not alone. Fish die-offs have been reported in waterways throughout the United States. Last September, thousands of white bass died in the Arkansas River with no clear explanation. Beginning in 2008, fish kills and fish with lesions were seen in the upper James River, and lesions were seen on the Jackson and Cowpasture rivers in Virginia as well. Intersex fish also have turned up in the Great Lakes and the Mississippi River.

Laurie Tenace
Environmental Specialist III
Waste Reduction Section
Florida Department of Environmental Protection
2600 Blair Stone Rd., MS 4555
Tallahassee FL 32399-2400
P: 850.245.8759
F: 850.245.8811
Laurie.Tenace at dep.state.fl.us<mailto:Laurie.Tenace at dep.state.fl.us>
Mercury: http://www.dep.state.fl.us/waste/categories/mercury/default.htm
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Pharmaceuticals: http://www.dep.state.fl.us/waste/pharm/

Please take a few minutes to share your comments on the service you received from the department by clicking on this link Copy the url below to a web browser to complete the DEP survey: http://survey.dep.state.fl.us/?refemail=Laurie.Tenace@dep.state.fl.us

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----- Message from "Volkman, Jennifer (MPCA)" <jennifer.volkman at state.mn.us<mailto:jennifer.volkman at state.mn.us>> on Thu, 26 Jul 2012 19:08:57 +0000 -----
To:

"pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>" <pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>>

Subject:

RE: [Pharmwaste] What's in the Water We Drink - long article about DC's water

I agree it is difficult to make sense of all of this, without freaking people out or having them just get bored reading about parts per bazillion of expialidocious. I've been in the HHW program for 17 years and I have to say that the pharms studies finally got to me, along with studies of ingredients in personal care products. I have finally made changes, taking far less OTC pain relievers, refusing antibiotic treatment for viruses and consulting various websites to find alternative PCPs. I think this kind of change is good. I figure after nearly 50 years of exposure to everything, it probably won't make a significant difference to my health, etc. but at least I'm supporting less toxic product manufacturers when I can.

BUT ALL THAT RAMBLING ASIDE: HERE'S YOUR TOXICOLOGIST TO EXPLAIN ALL OF THIS :)

Dr. Linda Birnbaum, toxicologist and director of the NIEHS (partial credentials here: http://www.nih.gov/news/health/dec2008/niehs-03.htm ), speaks on these impacts and the latest research and analytical advances at the link below. The first 7 minutes are introductions that you can skip. The presentation starts slow and the video isn't superb, but it gets really interesting when she starts to talk about the correlations between these small doses and their impacts and the interesting technology that is available to determine them. Her goal is to be able to explain these correlations in a way that a relatively intelligent 6th grader can understand it all--this is what she told me afterwards--and I think she does a good job of it.

What I think she proves, or makes us ponder, is that the timing of the dose is as critical as the magnitude.

Her presentation was sponsored by the University of Minnesota Center for Science, Technology & Public Policy, in partnership with the School of Public Health, Environmental Science Division, Consortium on Law and Values, Environmental Initiative, Minnesota Pollution Control Agency (MPCA) and Minnesota Department of Health (MDH).
http://mediamill.cla.umn.edu/mediamill/display/158978

JV

-----Original Message-----
From: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us> [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Miller, Christine M.
Sent: Thursday, July 26, 2012 1:29 PM
To: Fredrick L. Miller; pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Subject: RE: [Pharmwaste] What's in the Water We Drink - long article about DC's water

Amen!

Christine Miller l Recycling Coordinator
1419 Holland Rd. l Appleton, WI 54911
Phone: 920-968-5721 l Fax: 920-788-4130
www.RecycleMoreOutagamie.org<http://www.RecycleMoreOutagamie.org>

-----Original Message-----
From: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us> [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Fredrick L. Miller
Sent: Thursday, July 26, 2012 1:26 PM
To: pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Subject: RE: [Pharmwaste] What's in the Water We Drink - long article about DC's water

"evidence suggests that the same contaminants that caused massive fish kills and deformities in recent years are linked to increases in obesity, diabetes, autism, cancer, and other disorders-and that medications and products we use every day might contribute to the problem"

I'm hoping someone way smarter than me in the field of toxicology can help me with a question.

We've heard since the time of Paracelsus "the dose makes the poison" yet we accept statements such as the one above at face value. How is it consuming such dilute levels of substances can cause all these ills while consuming much higher concentrations is considered therapeutic? Shouldn't we be much more concerned about consuming and applying the prescriptions, potions, lotions, and neat substances in full strength? After all, that "witch's brew" comes from our home to begin with. We dose ourselves there with little to no regard for interaction. There is no agency watching out for our safety when it comes to considering what happens when we mix our medications with our shampoos, perfumes, household cleaners, plasticizers, fuels, etc. in the home yet we're all wrapped around the axle about a few PPT of the stuff in our drinking water. Isn't that a bit like having our cart before our horse?

Fred

P.s. I get that the fish and frogs can't protect themselves but using the drinking water concentrations as the lead-off for the story just strikes me as sensationalism and fearmongering.

-----Original Message-----
From: pharmwaste-bounces at lists.dep.state.fl.us<mailto:pharmwaste-bounces at lists.dep.state.fl.us> [mailto:pharmwaste-bounces at lists.dep.state.fl.us] On Behalf Of Tenace, Laurie
Sent: Wednesday, July 25, 2012 4:57 AM
To: pharmwaste at lists.dep.state.fl.us<mailto:pharmwaste at lists.dep.state.fl.us>
Subject: [Pharmwaste] What's in the Water We Drink - long article about DC's water

Much more at the link.

http://www.washingtonian.com/articles/people/whats-in-the-water-we-drink-2/

Washington's tap water, most of which comes from the Potomac River, meets or exceeds federal water-quality standards. But new pollutants have emerged that are not removed by current water-purification technology. Evidence suggests that the same contaminants that caused massive fish kills and deformities in recent years are linked to increases in obesity, diabetes, autism, cancer, and other disorders-and that medications and products we use every day might contribute to the problem.

Of all the natural resources in the Washington area, none is more important than the potomac river. Besides the beauty and recreation it provides, the area pulls nearly 400 million gallons of water a day out of it-about 90 percent of our drinking water.

In some ways, the Potomac is cleaner today than it was 40 or 50 years ago. Back then, people were warned not to swim in the river or eat fish from it; a tetanus vaccination was recommended for anyone who did swim there. On many days, you could smell the Potomac before you saw it.

Improvements in wastewater treatment and conservation upgraded the water quality of the river, which wends its way nearly 500 miles from its origin in the Appalachian Plateau to Point Lookout, Maryland, where it empties into the Chesapeake Bay. These efforts helped reduce major pollutants-such as nitrogen and phosphorous from fertilizers, pesticides, and soaps-that fed algae, rootless plant-like organisms that grow in sunlit water. Algae blooms-rapid accumulations of microscopic algae in water that can stretch for miles-deplete the water of oxygen and release harmful toxins. They can virtually destroy a river if left to grow unchecked.

Despite this progress, the river is not "clean." In 2011, the Potomac Conservancy, an organization that monitors the river, gave the Potomac a grade of D, a drop from the D-plus the organization assigned it in 2007. The conservancy noted that more than a third of the estimated 10,000 stream miles in the Potomac watershed are threatened or impaired.

Even so, the drinking water in the Washington area is closely monitored and meets or exceeds every Environmental Protection Agency water-quality standard. But as some of the old pollutants have been removed from the river, new ones have emerged that are not removed by current technology and may be harmful to human health, especially for the very young.

This emerging class of contaminants, called endocrine-disrupting compounds (EDCs), a variety of natural and manmade chemicals from many sources, first came to light in a dramatic way in the summer and fall of 2002 with massive fish kills along the south branch of the Potomac River in West Virginia, about 200 miles upstream from DC. Some of the contaminants are new, and others have been discovered recently because new measuring techniques permit scientists to identify EDCs in minute quantities.

Says Luke Iwanowicz, a scientist with the US Geological Survey: "Many of these emerging contaminants have been off our radar until now, mostly because we did not have the ability to detect them."